Drug Companies Abandon Alzheimer’s Disease Research

Alzheimer’s Epidemic Buried Under Inaccurate Death Certificates

By Helane Shieldscshields@tds.net

The most common conventional causes of death in industrialized countries are (1.) cardiovascular disease,(2.) cancer, (3.) Alzheimer’s disease and (4.) accident (in that order). Alzheimer’s victims usually die of pneumonia, a lung condition or a cerebro-vascular condition — so Alzheimer’s victims are often declared to die of other causes.

Alzheimer's disease prevention

Best’s opening statement not only highlights the importance of Alzheimer’s as a major cause of death but also very clearly sets forth the problem error in recording the cause of death. It seems rather clear that this is obviously a major reason for the inadequate funding of research for finding the cause and a cure for Alzheimer’s disease. The number of deaths due to Alzheimer’s is grossly understated on official records.

“My great-grandfather died from “Senility.” My grandmother is way, way, way into dementia-Alzheimer’s, who could no longer speak, didn’t know any of us any longer, died of “heart failure.” My aunt, who no longer recognized anyone in her family … died of heart failure. So you’re absolutely right … it isn’t getting its dues as far as cause of death.”

Alzheimer's disease prevention

Drug companies abandon Alzheimer’s research  

Some of Australia’s leading experts on Alzheimer’s disease say an alarming number of drug companies are abandoning research into drug treatments for dementia. Despite huge advances in neuro-imaging and diagnostic techniques, there’s been little progress when it comes to drugs to fight the disease. Pharmaceutical companies now in retreat cite the huge cost of research and the failure of drug trials to date.’

Will Pharma Companies Get Out of Alzheimer’s Disease R&D?

“Clinical trial results in Alzheimer’s Disease (AD) reported over the past few weeks have been disappointing to both patients and the academic community. The failure of both bapineuzumab (Pfizer/Johnson & Johnson) and solanezumab (Eli Lilly) to improve cognitive function has shown the difficulties inherent in trying to develop drugs to treat AD.”

 Sanofi Abandons Alzheimer’s Research

“Science isn’t advanced enough to justify the costs to develop a [Alzheimer’s] drug,” says Sanofi CEO, Chris Viehbacher.”

“I think we have to do a lot more basic science work to understand what’s going on,” Viehbacher said in the interview at an industry event in San Diego. “We really, at best, partially understand the cause of the disease. It’s hard to come up with meaningful targets.”

Drug companies ‘giving up’ on Alzheimer’s treatment after series of expensive failed trials

Leading pharmaceutical companies are ‘giving up’ on a cure for Alzheimer’s after the failure of several high-profile trials. “Drug firms are scaling down the search for new Alzheimer’s treatments after spending millions on late-stage trials which have collapsed in the past five years.

“Last month Pfizer and Johnson & Johnson pulled the plug on the experimental drug bapineuzumab after the failure of two high-profile clinical trials.’

Prusiner prions Nobel Prize

Scientists who agree with Nobel Laureate Stanley Prusiner that Alzheimer’s is a prion disease:

Manuelidis, et al, 1989; Bendixen, 1996; Boller, et al, 1989, 1995; Harrison, 1991; Teixeira, 1995;  Warren, et al, 2005, Glenn Millhauser, professor of chemistry and biochemistry at UCSC.

Posted in Causes, Prevention, Prion Disease, Research, Treatments | Tagged | Leave a comment

Mad Cow Prions In Your Vegetables

Sewage Sludge Puts Food, Water Supplies In Jeopardy

By Helane Shields, email hshields@tds.net

Infectious prions are in the sewage sludge being used to fertilize food crops across America and around the world. So-called biosolids and the reckless dumping of unregulated toxic waste are contributing to a global spike in neurodegenerative disease among people, wildlife and livestock.

biosolids land application safety

In 1981, the Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) cut a deal to dispose of sewage sludge as a soil amendment to grow human and animal crops, including wheat, corn and soybeans (basic ingredients in all of the food lining supermarket shelves), and sorgum (animal feeds). A recent study confirms that plants uptake and transport prions.

Prions are indestructible infectious proteins in brains which cause mad cow disease, Alzheimer’s, Chronic Wasting Disease (in deer), and other human and animal diseases.   Temperatures exceeding 1800 F are necessary to reduce prion infectivity. Cooking, boiling, autoclaving, etc. do not inactivate prions.

Prusiner prions Nobel Prize

Prion disease victims shed infectious prions in their urine and feces. The Alzheimer’s epidemic in the United States has claimed over 6 million victims who are excreting infectious prions into public sewers.   Wastewater treatment plants produce 7 million metric tons each year of the sewage sludge (biosolids), which contains nitrogen and phosphorus – hence, its disposal on land as fertilizer is the cheapest way to get rid of it.

Alzheimer's disease contagion

Alzheimer’s disease is vastly underreported. In fact, most death certificates list pneumonia as the cause of death when people die of Alzheimer’s disease. Parkinson’s – another prion disease – has claimed over a million victims. Autism, another epidemic which afflicts children, may also be a prion disease. Thus, the human sources of prions in sewage sludge are enormous.

sewage sludge land application LASS

Please take a look at these two files for more detail. 

FDA petition

Alzheimer’s Disease Transmission

Alzheimer's disease diagnosis

Helane Shields

Email to Helane Shields athshields@tds.net

Posted in Alzheimer's and diet connected, Causes, Mad Cow Disease, Prevention, Sewage | Tagged , , , | Leave a comment

Alzheimer’s Disease Caused By Mismanaged Sewage, Biosolids, Wastewater

Neurological Disease Spreading To Food, Water Supplies via Sewage

Approximately 44 million people around the world already have Alzheimer’s disease and other forms of dementia. It’s the fastest-growing cause of death in the world.

Alzheimer’s disease is a member of an aggressive family of neurodegenerative diseases known as Transmissible Spongiform Encephalopathy (TSE). The operative word is “transmissible.” Related diseases are killing wildlife and livestock. The TSE epidemic represents an environmental nightmare that threatens every mammal on Earth.

Alzheimer's disease caused by biosolids

TSEs include Alzheimer’s disease, Creutzfeldt-Jakob disease, mad cow disease and chronic wasting disease in deer. Few, if any, mammals are immune. There is no cure and there is no species barrier.

TSEs are caused by a deadly protein called a prion (PREE-on). Prion disease is unstoppable and the pathogen spreads through bodily fluids and cell tissue. Prions linger in the environment, homes, hospitals, nursing homes, dental offices, restaurants and many other places infinitely. They migrate, mutate, multiply and kill with unparalleled efficiency. Thanks to modern sewage disposal practices, prions are building up in our water supplies. They also are contaminating our crops, golf courses, parks and yards.

Prions defy all attempts at sterilization and inactivation. Victims of the disease can spread the disease even further via bodily fluids and cell tissue. Victims often are contagious long before they appear sick. Their saliva, urine, blood and feces help spread the pathogen further as they struggle to survive.

Dr. Stanley Prusiner earned a Nobel Prize in 1997 for identifying, naming and studying deadly prions. President Obama awarded Prusiner the National Medal of Science in 2010 to recognize the importance of his research. The importance of his research continues to unfold.

prions and prion disease

Barack Obama honors Dr. Stanley Prusiner for his research on prions and prion disease.

In June 2012, Prusiner confirmed that Alzheimer’s, Parkinson’s, Huntington’s and even ALS are prion diseases similar, if not identical, to CJD in people, mad cow disease in livestock and chronic wasting disease in wildlife. The variations in disease progression could be due to genetics in the patients or mutations in the prion, not different diseases entirely. Prion disease is prion disease.

Although there are many factors contributing to the prion disease epidemic, many lethal pathways are being mismanaged around the globe. As such, we are recycling the pathogen that causes Alzheimer’s right back into our food and water. We’re dumping these killer proteins on crops, parks, golf courses, ski areas and school grounds. Rain and irrigation spread them throughout our communities and watersheds. We’re dumping prions into our food and water supplies with foolish sewage management practices.

Prions Found In All Bodily Fluids, Tissue

A new study confirms that people and animals dying of prion disease are contaminating the environment around them with a deadly and unstoppable protein found in their bodily fluids. Claudio Soto, PhD, professor of neurology and director of the George and Cynthia W. Mitchell Center for Alzheimer’s Disease and Other Brain Related Illnesses at the University of Texas Medical School in Houston, and his colleagues recently found prions in urine. The study has been published in the August 7 issue of the New England Journal of Medicine.

The good news is that the research offers hope for earlier diagnosis among the millions of people impacted around the world. The discovery can promote earlier intervention and better disease management. It also can help develop screens to protect our blood supplies from donors with prion disease.

The bad news is that prions in urine, mucas, feces and blood underscore the environmental nightmare associated with Alzheimer’s, Creutzfeldt-Jakob (CJD), Parkinson’s, Huntington’s and prion diseases among livestock and wildlife. Although there are many causes for prion disease, many people and animals are contracting it from environmental exposure (food, water and soil) and then contaminating the environment even more with their own bodily fluids. Once victims die, carcasses also contaminate soil and water.

“This is the first time that prions have been detected in human urine,” Dr. Soto told Neurology Today.

Dr. Claudio Soto prion research

Soto failed to reference urine and blood studies performed earlier by Ruth Gabizon in 2001 and Reichl in 2002. These studies also detected prions in bodily fluids. Despite that detail, Soto’s findings can help focus global attention on the exploding prion problem.

Additional research has determined that the prion pathogen spreads through feces, saliva, blood, milk, soil, water and the tissue of infected animals and humans. If a single person with prion disease discharges bodily fluids or feces into a public sewer system, thatsewage system is permanently infected and the amount of contamination will multiply and intensify daily. Everything discharged from that sewage system—reclaimed waterand biosolids—can spread the contamination even further.

Once a prion reaches the soil, that soil is permanently contaminated and the entire watershed (water) below that point is at risk forever. If your food and water is generated in that watershed, you have a higher risk of contracting prion disease with every sip of water or every bite of food produced locally.

With the help of weather, prions can migrate through wind and water. Rain and snow can rinse them into surface water, groundwater, streams, ponds, lakes, and oceans. Wildlife, livestock and humans can ingest prions from soil, water and food. We can’t afford to take the risk of further contaminating entire watersheds – increasing the pathway to humans, livestock, and wildlife downstream.

This transmissible family of disease is unstoppable for many reasons. In addition, once items are exposed to victims of prion disease, they can never be sterilized again.

Because of these factors and others, we have an epidemic of prion disease exploding around the world right now. The epidemic is worse in some regions of the world than others. For example, the death rate for Alzheimer’s is higher in Finland than any other country in the world. Iceland and the United States are runners up. In fact, the death rate for Alzheimer’s is higher in Washington state than any other known region in the world. These vast discrepancies can only be explained by environmental factors, including food, water and air pathways. Sewage disposal that contaminates local food and water supplies is likely part of the problem.

Alzheimer’s and Creutzfeldt-Jakob disease are indistinguishable. They are essentially the same disease. Medical professionals cannot tell the difference and it’s commonly known in the medical industry that the diagnoses are only a guess and that misdiagnoses are common—if there’s even a substantial difference between Alzheimer’s and CJD. It appears that CJD is caused by a more aggressive mutation of prion than Alzheimer’s, but a deadly prion is a deadly prion. There is no reason to believe that some prions behave differently than others in disease transmission and progression.

The urine and sewage connection helps explain why the global epidemic is exploding. More than 44 million people around the world are known to have these neurodegenerative diseases today. Millions more have the disease, but don’t know it, yet. In addition to these people, millions of infected people around the world have used our sewage systems over the past century. Millions more are using them today. It’s impossible to neutralize or stop prions in even the most sterile environments, including hospitals. It’s ludicrous to think that treated sewage water or biosolids are prion-free. Especially since prions from people are much more infectious than those found in other species (prions become more aggressive as they work their way up the food chain).

The U.S. Environmental Protection Agency (EPA) has confirmed that prions are in sewage and that there has been no way to detect them or stop them. As such, the EPA has never issued guidance on prion management within sewage processing plants. This lack of directive allows budget-strapped states and counties to regulate the practices in a variety of ways that best suit local municipalities and industries.

Dr. Soto’s test changes that equation. Now, the EPA can’t plead ignorance to the dangers of prions in biosolids and reclaimed sewage water. Sewage dumped at sea must be reconsidered. Prions should again be classified as a select agent by the U.S. Department of Homeland Security and the Center for Disease Control. Similar measures should be enacted around the world immediately. Failure to act responsibly is suicide.

Unfortunately, testing will confirm that every sewage system in the world has served people with Alzheimer’s disease and CJD. As such, prions have been incubating, multiplying and migrating out of these systems for many years. The problem is intensifying within and beyond these sewage systems every day.

According to the U.S. EPA, “Prions are extremely resistant to inactivation by ultraviolet light, irradiation, boiling, dry heat, formaline, freezing, drying and changes in pH. Methods for inactivating prions in infected tissues or wastes include incineration at very high temperatures and alkaline hydrolysis.” They didn’t mention hydrogen peroxide, which is how some toilet-to-tap programs hope to kill deadly prions.

The EPA National Water Research Compendium 2009-2014 lists prions eight times as an emerging contaminant of concern in sewage sludge (biosolids), water and manure. The EPA issued what it calls the “Sludge Rule,” which basically disclaims any responsibility for its questionable risk assessments regarding biosolids. The EPA reserves the right to adjust these risk assessments, however, as the test of time disproves its pseudo-science.

Prion researcher Dr. Joel Pedersen, from the University of Wisconsin, found that prions become 680 times more infective in certain soils. Pedersen’s research also found that sewage treatment does not inactivate prions.

“Our results suggest that if prions enter municipal wastewater treatment systems, most of the agent would bond to sludge, survive anaerobic digestion, and be present in treated biosolids,” Pedersen said. “Land application of biosolids containing prions represents a route for their unintentional introduction into the environment. Our results emphasize the importance of keeping prions out of municipal wastewater treatment systems. Prions could end up in sewage treatment plants via slaughterhouses, hospitals, dental offices and mortuaries just to name a few of the pathways. The disposal of sludge represents the greatest risk of spreading prion contamination in the environment. Plus, we know that sewage sludge pathogens, pharmaceutical residue and chemical pollutants are taken up by plants and vegetables.”

“Since it’s unlikely that the sewage treatment or pellet production processes can effectively deactivate prions, adopting measures to prevent the entry of prions into the sewer system is advisable,” said the Toronto Department of Health, November 2004.

Meanwhile, we’re spreading tons of biosolids (sewage sludge) on farmland every day to produce our food. Organic food operations, including fruits, vegetables, meat and dairy are not immune to prion exposure. Research confirms that plants uptake prions and prions certainly contaminate leafy matter and the skin of fruits and vegetables upon contact.

We’re dumping biosolids on parks and golf courses and our backyards where we live and play. Coastal cities and ocean vessels dump their sewage right into the ocean, where prions can enter the food chain again, while washing back on our favorite beaches.

We’re dumping millions of tons of contaminated sewage into the oceans, rivers and on cropland around the world every day. We’re spraying reclaimed wastewater on our parks, golf courses and crops. In some cases, people are drinking reclaimed wastewater that has been recycled to their taps. Municipalities, water companies and sewage districts face new liabilities as never seen before.

 

Read The Full Story About prion Disease Cause http://alzheimerdisease.tv/alzheimers-disease-spreading-faster-via-biosolids-reclaimed-water/

Posted in Alzheimer's and diet connected, Causes, Creutzfeldt-Jakob Disease, Prevention, Prion Disease, Sewage | Tagged , | Leave a comment

Reused Water, Biosolids Adding Fuel To Alzheimer’s Disease Epidemic

Deadly Proteins Unstoppable In Biosolids, Reused Water

San Diego’s City Council approved plans to reuse sewage water into drinking water. It’s a growing trend that short-sells a proven health risk associated with deadly proteins.

In my opinion, San Diego joined a growing global movement in what could become a human health disaster. The move could be a death sentence for millions of people who will drink reclaimed wastewater. That same water will contaminate their homes, gardens and offices with a highly contagious and unstoppable pathogen called a prion–an infectious form of protein. The exposure can cause neurological disorders in mammals, including Alzheimer’s disease.

Alzheimer's disease spreading through food and water

Alzheimer’s disease is spreading through food and water. Mismanaged sewage is part of the problem.

The project, dubbed Pure Water San Diego, is expected to provide more than a third of the city’s potable water by 2035. When Pure Water is built out in 20 years, it is should generate 83 million gallons a day of “clean” water.

The system starts with micro-filtration, where rows of plastic tubes and straws filter out microbes and other contaminants. The big stuff.

The water then goes through reverse-osmosis to screen out organic material, salts and other solids. But all pathogens still are essentially untreated.

The last step is a combination of ultraviolet light and hydrogen peroxide to kill anything left. Pathogens resistant to UV light or hydrogen peroxide are destined for your tap.

As any surgeon worth his or her salt can tell you, UV light and hydrogen peroxide can kill many things if properly exposed, but they can’t kill a prion. In fact, there is not any known treatment in the world that is 100 percent effective against deadly prions in any environment, especially water. Hospitals safely discard surgical instruments used on patients with prion disease. Prions are more likely to migrate, mutate and multiply than be neutralized (they aren’t a virus or bacteria, so they can’t be killed).

The “treated” water from the proposed San Diego system could be mixed into the San Vicente Reservoir and piped to customers, or the city could route the water directly into the distribution system. Once exposed to deadly prions, the waterways will be contaminated forever–serving as incubators and distributors of neurological disorders, including Alzheimer’s disease.

reused wastewater and public health threat

Is it really safe to drink reclaimed human sewage? Not if you hope to avoid deadly neurological disorders. prions are unstoppable.

The Orange County water reclamation program was recently featured on CBS’ 60 Minutes. Reporter Lesley Stahl bravely drank a sample of treated sewage water during the story. As she explained, San Diego won’t be the first to drink its own sewage. A number of other cities around the world have already sold their souls down the river based on half-truths and misinformation. Orange County, for example, recycles 70 million gallons a day to potable. It’s expanding capacity to 100 million gallons per day.

The Problem With Prions and Prion Disease

If not for one tiny detail, I would be more open-minded and supportive of the practice of recycling wastewater. That microscopic detail is called a prion—the deadly and unstoppable protein behind the exploding Alzheimer’s epidemic, mad cow disease and other neurological disorders that are killing millions of people, wildlife and livestock around the world.

A new study confirms that people and animals dying of prion disease are contaminating the environment around them with a deadly and unstoppable protein found in their bodily fluids. Claudio Soto, PhD, professor of neurology and director of the George and Cynthia W. Mitchell Center for Alzheimer’s Disease and Other Brain Related Illnesses at the University of Texas Medical School in Houston, and his colleagues recently found prions in urine. The study has been published in the August 7 issue of the New England Journal of Medicine.

The bad news is that prions in urine underscore the environmental nightmare associated with Alzheimer’s, Creutzfeldt-Jakob (CJD), Parkinson’s, Huntington’s and prion diseases among livestock and wildlife. Although there are many causes for prion disease, many people and animals are contracting it from environmental exposure (food, water and soil) and then contaminating the environment even more with their own bodily fluids. Once victims die, carcasses also contaminate soil and water.

“This is the first time that prions have been detected in human urine,” Dr. Soto told Neurology Today.

Soto failed to reference urine and blood studies performed earlier by Ruth Gabizon in 2001 and Reichl in 2002. These studies also detected prions in bodily fluids. Despite that detail, Soto’s findings can help focus global attention on the exploding prion problem.

prions and prion disease

Barack Obama honors Dr. Stanley Prusiner for his research on prions and prion disease.

Dr. Stanley Prusiner earned a Nobel Prize in 1997 for identifying, naming and studying deadly prions. President Obama awarded Prusiner the National Medal of Science in 2010 to recognize the importance of his research.

In June 2012, Prusiner confirmed that Alzheimer’s, Parkinson’s, Huntington’s and even ALS are prion diseases similar, if not identical, to CJD in people, mad cow disease in livestock and chronic wasting disease in wildlife. The variations in disease progression could be due to genetics in the patients or mutations in the prion, not different diseases entirely.

Additional research has determined that the prion pathogen spreads through feces, saliva, blood, milk, soil, water and the tissue of infected animals and humans. If a single person with prion disease discharges bodily fluids or feces into a public sewer system, that sewage system is permanently infected and the amount of contamination will multiply and intensify daily. Everything discharged from that sewage system—reclaimed water and biosolids—can spread the contamination even further.

Once a prion reaches the soil, that soil is permanently contaminated and the entire watershed below that point is at risk forever. If your food and water is generated in that watershed, you have a higher risk of contracting prion disease.

With the help of weather, prions can migrate through wind and water. Rain and snow can rinse them into surface water, groundwater, streams, ponds, lakes, and oceans. Wildlife, livestock and humans can ingest prions from soil, water and food. We can’t afford to take the risk of further contaminating entire watersheds – increasing the pathway to humans, livestock, and wildlife downstream.

Because of these factors and others, we have an epidemic of prion disease around the world right now. The epidemic is worse in some regions of the world than others. For example, the death rate for Alzheimer’s is higher in Finland than any other country in the world. Iceland and the United States are runners up. In fact, the death rate for Alzheimer’s is higher in Washington state than any other known region in the world. These vast discrepancies can only be explained by environmental factors, including food, water and air pathways. Sewage disposal that contaminates local food and water supplies is likely part of the problem.

The scientific name for prion disease is Transmissible Spongiform Encephalopathy (TSE). The operative word is “transmissible.” TSEs include Alzheimer’s, mad cow, Creutzfeldt-Jakob disease (CJD), chronic wasting, Huntington’s, scrapie and possibly Parkinson’s. This transmissible family of disease is unstoppable for many reasons. In addition, once items are exposed to victims of prion disease, they can never be sterilized again.

The urine and sewage connection helps explain why the global epidemic is exploding. More than 44 million people around the world are known to have these neurodegenerative diseases today. Millions more have the disease, but don’t know it, yet. In addition to these people, millions of infected people around the world have used our sewage systems over the past century. Millions more are using them today. It’s impossible to neutralize or stop prions in even the most sterile environments, including hospitals. It’s ludicrous to think that treated sewage water or biosolids are prion-free. Especially since prions from people are much more infectious than those found in other species (prions become more aggressive as they work their way up the food chain).

The U.S. Environmental Protection Agency (EPA) has confirmed that prions are in sewage and that there has been no way to detect them or stop them. As such, the EPA has never issued guidance on prion management within sewage processing plants. This lack of directive allows budget-strapped states and counties to regulate the practices in a variety of ways that best suit local municipalities and industries.

Dr. Soto’s test changes that equation. Now, the EPA can’t plead ignorance to the dangers of prions in biosolids and reclaimed sewage water. Sewage dumped at sea must be reconsidered. Prions should be classified as a select agent again by the U.S. Department of Homeland Security and the Center for Disease Control. Similar measures should be enacted around the world immediately. Failure to act responsibly is suicide.

Unfortunately, testing will confirm that every sewage system in the world has served people with Alzheimer’s disease and CJD. As such, prions have been incubating, multiplying and migrating out of these systems for many years. The problem is intensifying within and beyond these sewage systems every day.

According to the U.S. EPA, “Prions are extremely resistant to inactivation by ultraviolet light, irradiation, boiling, dry heat, formaline, freezing, drying and changes in pH. Methods for inactivating prions in infected tissues or wastes include incineration at very high temperatures and alkaline hydrolysis.” They didn’t mention hydrogen peroxide.

“Since it’s unlikely that the sewage treatment or pellet production processes can effectively deactivate prions, adopting measures to prevent the entry of prions into the sewer system is advisable,” said the Toronto Department of Health, November 2004.

The EPA National Water Research Compendium 2009-2014 lists prions eight times as an emerging contaminant of concern in sewage sludge (biosolids), water and manure.

The Sludge Rule Overrules The Golden Rule

The EPA issued what it calls the “Sludge Rule,” which basically disclaims any responsibility for its questionable risk assessments regarding biosolids. The EPA reserves the right to adjust these risk assessments, however, as the test of time disproves its pseudo-science.

Prion researcher Dr. Joel Pedersen, from the University of Wisconsin, found that prions become 680 times more infective in certain soils. Pedersen’s research also found that sewage treatment does not inactivate prions.

“Our results suggest that if prions enter municipal wastewater treatment systems, most of the agent would bond to sludge, survive anaerobic digestion, and be present in treated biosolids,” Pedersen said. “Land application of biosolids containing prions represents a route for their unintentional introduction into the environment. Our results emphasize the importance of keeping prions out of municipal wastewater treatment systems. Prions could end up in sewage treatment plants via slaughterhouses, hospitals, dental offices and mortuaries just to name a few of the pathways. The disposal of sludge represents the greatest risk of spreading prion contamination in the environment. Plus, we know that sewage sludge pathogens, pharmaceutical residue and chemical pollutants are taken up by plants and vegetables.”

Meanwhile, we’re spreading tons of biosolids (sewage sludge) on farmland every day to produce our food. Organic food operations, including fruits, vegetables, meat and dairy are not immune to prion exposure.

We’re dumping biosolids on parks and golf courses and our backyards where we live and play. Coastal cities and ocean vessels dump their sewage right into the ocean, where prions can enter the food chain again, while washing back on our favorite beaches.

We’re dumping millions of tons of contaminated sewage into the oceans, rivers and on cropland around the world every day. We’re spraying reclaimed wastewater on our parks, golf courses and crops. In some cases, people are drinking reclaimed wastewater that has been recycled to their taps. Municipalities, water companies and sewage districts face new liabilities as never seen before.

The new urine study primarily references what is called variant CJD (vCJD is the supposed strain of prion that causes mad cow disease). I argue that a deadly prion is a deadly prion and all prion diseases should be managed assuming that prions are in the urine of all victims. There is no species barrier. There is no cure. There is no reason to assume that prion diseases referred to as Alzheimer’s, CJD, Parkinson’s, Huntington’s and others are different from each other.

Based on this premise, caregivers and family members must arm themselves with facts that can save their lives. Simple acts can expose family and caregivers to the prion contagion. For example, many household items, including utensils and dishes that belong to people who have Alzheimer’s and Huntington’s are likely infected from saliva. It’s unsafe for others to use these items and people should not donate them to charity.

Despite the mass confusion and concern regarding prion disease, protective and sterilization protocols for Alzheimer’s and CJD are not the same and millions of people are being exposed to prion disease because of false securities. CJD is just the tip of a deadly, incurable iceberg and we all should sit up and pay attention right now. We’re recklessly allowing caregivers and stakeholders to expose themselves and others to the problem.

Although there are multiple causes of, and pathways for, prion disease, reckless policies around the world are contributing to the unstoppable epidemic. It’s spreading further every day. Stakeholders must arm themselves with facts that can promote reform because all infected mammals shed infectious prions in their blood, saliva, mucus, urine and feces. Prions also have been found in milk. In essence, the entire body of a victim is contaminated and must be managed accordingly. That includes Alzheimer’s disease, Creutzfeldt-Jakob disease, Huntington’s disease and Parkinson’s disease.

https://www.academia.edu/9711886/Alzheimers_Disease_Fueled_By_Mismanaged_Sewage

Posted in Alzheimer's and diet connected, Causes, Prevention, Sewage | Tagged , , , | Leave a comment

Does Recycled Wastewater Cause Alzheimer’s Disease

Deadly Protein Unstoppable In Sewage

The San Diego City Council approved plans to recycle sewage water into drinking water this week. The move likely failed to account for a proven health risk.

In my opinion, San Diego joined a growing global movement in what could become a human health disaster. The move is a death sentence for millions of people who will drink reclaimed wastewater and contaminate their homes, gardens and offices with a highly contagious and unstoppable pathogen called a prion. The exposure can cause neurological disorders in mammals, including Alzheimer’s disease.

Pure Water San Diego human health threat

Is it really safe to drink reclaimed human sewage? Not if you hope to avoid Alzheimer’s disease.

The “treated” water from the proposed San Diego system could be mixed into the San Vicente Reservoir and piped to customers, or the city could route the water directly into the distribution system. Once exposed to deadly prions, the waterways will be contaminated forever–serving as incubators and distributors of neurological disorders, including Alzheimer’s disease.

The Orange County water reclamation program was recently featured on CBS’ 60 Minutes. Reporter Lesley Stahl bravely drank a sample of treated sewage water during the story. As she explained, San Diego won’t be the first to drink its own sewage. A number of other cities around the world have already sold their souls down the river based on half-truths and misinformation. Orange County, for example, recycles 70 million gallons a day to potable. It’s expanding capacity to 100 million gallons per day.

Alzheimer's caused by sewage

The Alzheimer’s disease epidemic. Sewage spreads the unstoppable pathogen.

Prions and Prion Disease

If not for one tiny detail, I would be more open-minded and supportive of the practice of recycling wastewater. That microscopic detail is called a prion—the deadly and unstoppable protein behind the exploding Alzheimer’s epidemic, mad cow disease and other neurological disorders that are killing millions of people, wildlife and livestock around the world.

A new study confirms that people and animals dying of prion disease are contaminating the environment around them with a deadly and unstoppable protein found in their bodily fluids. Claudio Soto, PhD, professor of neurology and director of the George and Cynthia W. Mitchell Center for Alzheimer’s Disease and Other Brain Related Illnesses at the University of Texas Medical School in Houston, and his colleagues recently found prions in urine. The study has been published in the August 7 issue of the New England Journal of Medicine.

Please Read The Rest Of The Story>: http://alzheimerdisease.tv/can-recycled-wastewater-cause-alzheimers-disease/

Posted in Causes, Creutzfeldt-Jakob Disease, Prevention, Prion Disease | Tagged , , | Leave a comment

Caregivers Warned To Treat Alzheimer’s As Transmissible Disease

Disease Deadly, Unstoppable

If one Alzheimer’s author and advocate is right, millions of caregivers and family members around the world are putting themselves and even others at risk while caring for Alzheimer’s patients. A new book by Crossbow’s Gary R. Chandler explains why some, if not all, forms of Alzheimer’s are contagious. Caregivers and family members must follow strict guidelines to avoid high-risk pathways.

Alzheimer's research

Alzheimer’s: A Survivor’s Guide explains that some, if not all, forms of dementia are contagious. This book explores Alzheimer’s as part of a protein epidemic. It makes several critical points and asks some challenging questions about a form of killer protein called a prion (pronounced PREE-on).

Alzheimer’s deaths in the U.S. alone increased 68 percent between 2000 and 2010. During that same time, deaths from other major diseases, including heart disease and cancer, decreased significantly. Most developed countries are making progress on all health fronts, except for Alzheimer’s and other forms of dementia. (Even autism could share a common thread.)

Meanwhile, government officials around the world are predicting that the numbers of living victims will triple, if not more, within a decade or two. Meanwhile, millions more will die each year of the deadly disease.

“In my opinion, Alzheimer’s and other neurodegenerative disorders such as Mad Cow disease, Creutzfeldt-Jakob disease and Chronic Wasting disease all are being mismanaged around the world,” Chandler said. “The outbreaks all started about the same time. All are deadly. None are curable. All are caused by deadly proteins. The correlations speak volumes. Plus, even the healthcare experts at hospitals continue exposing innocent patients to deadly prions. It’s happening more than is being reported — and quite a few are being reported.”

One of the reasons for alarm is that most doctors can’t tell the difference between Alzheimer’s and it’s more aggressive cousin Creutzfeldt-Jakob disease (CJD). CJD is indisputably contagious. CJD often is misdiagnosed as Alzheimer’s — if there is any difference at all. If for no other reason, Alzheimer caregivers should manage against the high rate of misdiagnosis. However, if Alzheimer’s is a prion disease as Nobel Laureate Stanley Prusiner suggests, that puts the disease in the family known as TSEs – transmissible spongiform encephalopathies. Note the first word of that phrase. This deadly family includes CJD, mad cow disease, scrapie and chronic wasting disease. The diseases are unstoppable as the victims contaminate their surroundings with urine, feces, saliva, mucas, blood, milk, and cell tissue. This isn’t science fiction.

For more information and to join our new Alzheimer’s advocacy campaign, contact Chandler at http://crossbowcommunications.com/crossbow-unveils-fundraiser-for-alzheimers-research/

Posted in Caregivers, Causes | Tagged | 1 Comment

Alzheimer’s Disease Being Recycled Via Human Sewage

There is definitely a connection between sewage and prion diseases. Deadly prions are in the blood, urine, feces, saliva and tissue of millions of infected people and animals. Sewage treatment cannot stop prions, which means that they survive the process and end up on golf courses and farms through reclaimed water and biosolids (sludge). Now, they are destined for more and more taps around the world through reclaimed water and “toilet to taps” programs.

sewage water and disease.

Recycling sewage water and disease–not a good idea.

Deadly prions are found in the urine, feces, blood, saliva and tissue of human and animals infected with prion disease, including Creutzfeldt-Jakob disease, Alzheimer’s, Chronic Wasting disease, and Mad Cow disease. Infected fluids from hospitals, dental offices, morgues, crematories, slaughterhouses, and more make it to many local sewage plants. Prions are unstoppable. Sewage treatment has little, if any effect on prions. Just ask the U.S. EPA. Therefore, prions survive and live on through sewage sludge and reclaimed water. Prion diseases are recycled when sewage sludge and reclaimed water are applied to crops, parks, golf courses and beyond. Many areas are even reclaiming sewage water and sending it to the taps in homes. This is a really bad idea.

When sewage is applied to land, the prions are washed into groundwater, creeks, rivers, lakes and oceans. A new study from the University of Wisconsin has found that plants (vegetables and crops used for animal feed) exposed to prions, become infected with prions and can transmit deadly prion disease. Therefore, applying human sewage from thousands of people infected with Alzheimer’s disease and Creutzfeldt-Jakob disease is transmitting deadly prions directly into our food and water supply. Cheers to Victoria, B.C. for having the vision and courage to reject the BS and pathogens being spread by the sewage industry and many regulators around the world. In fact, sewage sludge is likley contributing to the spread of Chronic Wasting disease.

Though not the only cause of prion disease, pissing in the proverbial pool in the age of a deadly prion epidemic is not a good idea. It’s time to rethink and reform sewage disposal policies around the world. The epidemic is real. More than 40 million people around the world have dementia now and it’s expected to get much worse. Prion diseases are always deadly. There is no prevention other than your wits. There is no cure. The book available on this website goes into much more detail.

By recycling disease with sludge and wastewater, the prion pathogen is making its way into drinking water and into food products. We have created Pandora’s “Lunchbox” with our sewage disposal practices alone. It’s time to reform these practices before the contamination spreads even further. Read more in the book and please advocate for the reform of sewage disposal practices.

For more information, visit www.AlzheimerDisease.TV

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Proteomics & Alzheimer’s Disease: Radio Interview

Keith & Russ talk with Dr. Oscar Alzate, Senior Director of Proteomics, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center in El Paso.  Alzate explains proteomics and how proteoms relate to Alzheimer’s.   He also engages Keith & Russ in a conversation about the restrictions of scientific research in America and whether it’s beneficial to the populace.

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Aired Nov. 24, 2013. 

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U.S. Finally Strengthens Rules To Slow Mad Cow Disease

Editor’s Note: In my opinion, this is a great step in the right direction, but sound science says that it’s too little too late. The contagion (prions) has already been released from Pandora’s Lunchbox and putting the lid back on will fail to stop the spread of deadly prion disease in people, wildlife and livestock. Yes, according to Nobel-Prize winner Stanley Prusiner, Alzheimer’s is a prion disease just like Mad Cow disease and Creutzfeldt-Jakob disease. That means that Alzheimer’s is highly contagious and that patients are infecting their world and our world. Caregivers deserve the truth for safety and to keep others safe. Well-informed doctors don’t want to touch patients with Alzheimer’s or CJD. Why don’t they bother telling others?

Prion pathways extend way beyond the food supply, but all efforts to contain the spread of deadly prions must be aggressive, coordinated and based on sound science–which says that prions can’t be stopped. Prion diseases kill everything in their path. Prion diseases cannot be cured. That’s called sobering science that needs serious action not token gestures.

The U.S. Department of Agriculture (USDA) issued new regulations Friday that align the federal protections against mad cow disease with international standards.

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The long-awaited rule, issued by the USDA’s Animal and Plant Health Inspection Service (APHIS), drew praise from lawmakers from both sides of the aisle, who said it would help to open more international markets to U.S. beef products.

The APHIS rule for bovine spongiform encephalopathy (BSE), also known as mad cow disease, uses internationally accepted trade standards set by the World Organization for Animal Health (OIE). Those standards will require APHIS to tailor its import policy for foreign countries on their risk classification, as determined the OIE.

The regulation, which will take effect 90 days after it is published in the Federal Register, also allows APHIS to conduct its own assessments.

“Making these changes will further demonstrate to our trading partners our commitment to international standards and sound science, and we are hopeful it will help open new markets and remove remaining restrictions on U.S. products,” said Dr. John Clifford, APHIS deputy administrator and chief veterinary officer.

Some countries have prohibited imports of U.S. cattle over 30 months old, basing the trade barriers on the absence of a comprehensive regulation hewing to international standards.

Among them is Mexico, traditionally one of the largest export markets for U.S. beef. Sen. Debbie Stabenow, chairwoman of the Senate Agriculture Committee, said the restriction is costing U.S. beef producers $100 million a year.

Stabenow (D-Mich.) said the regulation would help break down crucial trade barriers for American beef.

“Today’s actions will ensure U.S. beef producers can operate on a more level playing field and help grow our agriculture economy,” she said in a statement.

Sen. Chuck Grassley (R-Iowa), who had called since at least February of 2012 for the agency to act, also heralded the development. He said the new regulations would strengthen both the American industry’s position and that of the U.S. Trade Representative.

“Beef producers have been waiting years for the Department of Agriculture to issue the BSE comprehensive rule,” Grassley said in a statement. “When nations base their decisions on sound science, more markets will be expanded or opened to U.S. beef.”

Source: http://thehill.com/blogs/regwatch/business/189028-usda-hews-to-international-standards-on-beef-trade

Posted in Chronic Wasting Disease, Creutzfeldt-Jakob Disease, Mad Cow Disease, Prion Disease | Leave a comment

How to Prevent Alzheimer’s Disease—A Neurologist Speaks Out About Diet

Nutrition Can Prevent, Treat Alzheimer’s Disease

By Dr. Mercola

Alzheimer’s disease is at epidemic proportions, with 5.4 million Americans—including one in eight people aged 65 and over—living with the disease (40 million people have dementia globally). In the next 20 years, it is projected that Alzheimer’s will affect one in four Americans, rivaling the current prevalence of obesity and diabetes.

There is still no known accepted cure for this devastating disease, and no effective treatments. Alzheimer’s drugs are often of little to no benefit at all, which underscores the importance of prevention throughout your lifetime.

nutrition and Alzheimer's disease

Fortunately, Alzheimer’s prevention is actually easier than you might think. There’s exceptionally compelling research showing that your brain has great plasticity, which you control through your diet and lifestyle choices.

Here, Dr. David Perlmutter—probably the leading natural medicine neurologist in the US, from my perspective—shares his insights into this pervasive problem. I don’t know anyone who exceeds his level of expertise in traditional neurology and still shares the same philosophical orientation that I have.

He has a clinic in Naples, Florida, and he’s been very active in publishing his findings in peer-reviewed medical journals. He’s also a fellow of the American College of Nutrition, as am I.

“I have a very strong background in traditional neurology,” Dr. Perlmutter says. “As a neurologist for many years, I became more and more frustrated with our lack of ability to actually treat diseases. We were really only treating symptoms.

When I finally began to understand what the proximate cause of the various illnesses we were dealing with was, I realized that mainstream neurology, though I don’t want to sound too critical, really pays no attention to the causation part of the story.”

The Role of Grains in Disease Propagation

He realized an answer would never become apparent by simply writing prescriptions and hoping for the best. Instead, he began investigating the role of nutrition on brain health. Alzheimer’s, according to the RAND Corporation, is currently costing us some $200  billion a year, yet it is largely preventable. And virtually no one talks about that!

“This is a disease that is highly revenue-producing for mega factories of various so-called Alzheimer’s drugs,” Dr. Perlmutter says. “The point is there is no meaningful treatment in 2013. It is a disease predicated on lifestyle choices primarily, because of the high amount of carbohydrates/sugar that we now, as Western-culture individuals, are consuming.

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It’s a preventable disease. It surprises me at my core that no one’s talking about the fact that so many of these devastating neurological problems are, in fact, modifiable based upon lifestyle choices.”

Dr. Perlmutter specifically looked at the impact of gluten and casein, or wheat and dairy primarily, on autoimmune diseases. His New York Times Bestseller, Grain Brain, reveals his findings, the cornerstones of which are the powerfully toxic role of glucose (sugar) and carbohydrates in one’s diet.

He also stresses that gluten sensitivity is involved in most chronic disease, including those affecting the brain, because of how gluten affects your immune system. Unfortunately, many people, physicians included, still believe that if you don’t have celiac disease, gluten is fair game and you can eat as much of it as you like.

Full-blown Celiac disease, which is gluten sensitivity affecting your small intestine, affects an estimated 1.8 percent of people in Western cultures. But  gluten sensitivity may actually affect as much as 30 to 40 percent of all people, and according to Dr. Alessio Fasano at Massachusetts General Hospital,virtually all of us are affected to some degree.

This is because we all create something called zonulin in the intestine in response to gluten. This protein, found in wheat, barley and rye, makes your gut more permeable, which allows proteins to get into your bloodstream that would otherwise have been excluded. That then sensitizes your immune system and promotes inflammation and autoimmunity. This kind of gut permeability is also promoted by things like antibiotics and chlorinated water.

The Gut-Brain Connection is Critical to Understand

Once gluten sensitizes your gut, it then becomes more permeable and all manner of previously excluded proteins—including casein and other dairy proteins—have direct access to your bloodstream, thereby challenging your immune system.

“They’ve been talking about it for years and years (which is now just gaining traction in mainstream medicine) that our health really depends on maintaining a barrier of the intestine from the bloodstream,” Dr. Perlmutter says.

“We now understand that the so-called blood-brain barrier, or that barrier that keeps things out of the brain where they don’t belong, is also affected by gluten, according to new research. It’s a very exciting time when we recognize that our biggest exposure to the environment is actually the lining of our intestines – not our lungs, not our skin. We are in fact very much dependent on the microbiota, the bacteria living in the gut, to maintain our health.”

According to Dr. Perlmutter, much of our current disease burden stems from the fact that we are contaminating our immune systems with proteins to which the human immune system has never, in the history of humankind, been previously exposed to. While not discussed in this interview, a MAJOR factor is the development of genetically engineered (GE) grains, which are now pervasive in most processed foods sold in the US. These GE crops create proteins never before encountered in any natural grain or food, so GE grains deliver a double-whammy against your immune system. Food allergies clearly appear to be one of the most noticeable side effects of a GE-grain diet.

“We recognize that food is far more than protein, carbohydrates, fat, and micronutrients, and that food really does represent information. The foods that we consume are instructing our genes. Therefore, that’s a very empowering notion: you can change your genetic destiny based upon the food choices that you make,” Dr. Perlmutter says.

Dr. Natasha Campbell-McBride, another neurologist who has also done remarkable work in this area as a result of seeking a solution for her autistic son, came to the same conclusion discussed by Dr. Perlmutter. Essentially, preventing and treating neurological disorders requires severe restriction of gluten and casein. You also need to address your gut flora.

“With specific response to your comments about autism, we do know that some of the milk-related proteins tend to lead to antibody production in the brains of autistic children, blocking what’s called the folate receptor,” Dr. Perlmutter says. “One of the propositions is that there’s this blockage of the ability of folate to get into the brains of certain children, and this leads to all kinds of cognitive and neurocognitive issues.

The State University of New York has actually developed a screen for looking at folate receptor antibodies. We have found that to be actually very helpful… It’s a very exciting time for those of us not just in neurology but in all branches of medicine, who are suddenly realizing that we’ve come full circle. We’re now back to understanding that nutrition plays a pivotal role in the health of humans.”

Avoiding Dairy Does NOT Include Avoiding Dairy Fats

I believe it would be wise for most people to avoid pasteurized dairy (primarily casein but also other proteins) and gluten. That said, there are subgroups of people who are particularly prone to harm from these proteins, and as a rule must avoid them in order to maintain their health. Bear in mind that dairy fat like butter, which has virtually no protein, is not problematic and can be consumed even by those who are sensitive to milk proteins. As stated by Dr. Perlmutter:

“We need to eat fat. We’re suggesting a revolutionary dietary change, telling people they should go on this new diet—which is only the diet humans have eaten for the past 2.6 million years! We’ve always eaten fat. Fat is the most wonderful health-providing food that we can obtain in the human diet. Of course, we have to qualify that with what typeof fat you are eating.”

Beneficial health-promoting fats that your body—and your brain in particular—needs for optimal function include organic butter from raw milk, clarified butter called organic grass fed raw butter, olives, organic virgin olive oil and coconut oil, nuts like pecans and macadamia, free-range eggs, wild Alaskan salmon, and avocado, for example.

According to Dr. Perlmutter, our current dietary fat phobia “has absolutely been the cornerstone of our most common degenerative diseases of the day, including Alzheimer’s.” Why? Because when you cut dietary fat and keep protein about the same, you’re going to fill in the gaps with health-harming carbohydrate foods, predominantly grains.

“This whole grain goodness, as the US Department of Agriculture is trying to convince us we should focus on in terms of our dietary choices, is the cornerstone of our most devastating diseases. I mean, brain diseases like Alzheimer’s, cardiovascular disease, and obviously, what leads to them, diabetes, which is so prevalent in Western societies. Again, it’s the getting away from fat and the substitution with wheat- and corn-based carbohydrate (high-fructose corn syrup) that really, in my opinion, explains this huge explosion of degenerative conditions that are crippling us medically and crippling us economically as well,” he says.

“But the quality of the fat that we consume is absolutely fundamental. When we’re saying high-fat diet, we’re not talking about prepared foods on the Twinkie aisle at the grocery store that contain modified trans fats; hydrogenated fats that are clearly coffin nails. They’re a great risk for brain disorders, heart disorders, diabetes, etc. We’re talking about these beautiful, natural fats that we have been consuming for more than two million years.”

Recommended Tests to Evaluate Disease Risks

There are specific tests that can help you determine your level of sensitivity to dairy proteins like casein, as well as gluten. The most effective test for gluten sensitivity, according to Dr. Perlmutter, is a test called the Cyrex Array 3 test. Most laboratories, when you order a test for either gluten sensitivity or celiac disease specifically, will look for antibodies against just one type of gliadin. However, there are dozens of different types of gliadin that can incite immune reaction or immune reactivity. The Cyrex test looks at 24 different parameters of gluten sensitivity, which gives you a much clearer picture.

“Most commonly when I’m seeing patients, they’ve already had some form of preliminary gluten sensitivity test which was negative, and we find [out the truth] by doing the Cyrex test,” he says.

The same lab offers another test, Cyrex Array 4, which looks at cross-sensitivity in people who are gluten-sensitive. This test includes a dairy product panel as well as amaranth, spelt, quinoa, rice, coffee, chocolate, and other foods that may be cross-reactive with respect to gliadin. Two other tests recommended by Dr. Perlmutter that are potent predictors of Alzheimer’s disease specifically are:

  • Fasting blood sugar, as this is a powerful predictor of your risk for Alzheimer’s disease. In this interview, he discusses research showing a very direct correlation between your fasting blood sugar and the rate at which your brain shrinks.  The higher your fasting blood sugar, the greater your risk. Interestingly, brain shrinkage occurs at blood sugar levels that are currently considered within the normal range (90-100), and even small elevations of blood sugar directly correlate to increased risk for having shrinkage of your hippocampus, your memory center, which is the hallmark of Alzheimer’s disease.
  • Hemoglobin A1c. This is a marker of your average blood sugar over about a three-to four-month period of time. Again, there’s a striking correlation between hemoglobin A1c and the rate at which your brain is shrinking.

Both of these factors, your blood sugar and hemoglobin A1c, are entirely within your power to control, as they respond to dietary changes. Quite simply, you lower them by reducing your carbohydrate consumption. As stated by Dr. Perlmutter:

“You can absolutely control your blood sugar. It’s a lifestyle choice. Do you eat grain? Do you drink orange juice in the morning? Are you having cereal in the morning? Have you decided to go low-carb and high-fat? In the latter case, your hemoglobin A1c will come down, your fasting blood sugar will come down, and lo and behold, you have taken positive steps to reduce your risk of brain shrinkage.”

How the Science of Neuroplasticity Changes the Game

It’s important to realize that, despite what the media tells you, your brain is not “programmed” to shrink and fail as a matter of course as you age. We now know that every activity in which you engage—be it exercise, the foods you eat, the supplements you take, your personal relationships, your emotional state, your sleep patterns—all of these factors dramatically influence your genetic expression from moment to moment. Any given gene is not in a static “on” or “off” position. Neither are they deterministic. You may be a carrier of a gene that never gets expressed, simply because you never supply the required environment for it to turn on.

“We interact with our genome every moment of our lives, and we can do so very, very positively,” Dr. Perlmutter says. “Keeping your blood sugar low is very positive in terms of allowing the genes to express reduced inflammation, which increase the production of life-giving antioxidants. So that’s rule number one: You can change your genetic destiny.

Rule number two: you can change your genetic destiny to grow new brain cells, specifically in the hippocampus… Your brain’s memory center regenerates. You are constantly growing new brain cells into your 50s, 60s, 80s, and 90s – throughout your lifetime – through a process called neurogenesis.

That said, these two ideas come together because you can turn on your genes through lifestyle choices that enhance neurogenesis and that enhance regrowth of cells and expansion of your brain’s memory center. This was proven by researchers recently. They demonstrated that there are factors under our control that can make that happen.”

Lifestyle strategies that promote neurogenesis and regrowth of brain cells include the following. All of these strategies target a specific gene pathway called BDNF or brain-derived neurotrophic factor, which promotes brain cell growth and connectivity as demonstrated on MRI scans.

  • Exercise. In one year-long study, individuals who engaged in exercise were actually growing and expanding the brain’s memory center one to two percent per year, where typically that center would have continued to decline in size.
  • Reducing overall calorie consumption
  • Reducing carbohydrate consumption
  • Increasing healthy fat consumption
  • Increasing your omega-3 fat intake and reducing consumption of damaged omega-6 fats (think processed vegetable oils) in order to balance your omega-3 to omega-6 ratio. I prefer krill oil to fish oil here, as krill oil also contains astaxanthin, which appears to be particularly beneficial for brain health. As explained by Dr. Perlmutter, it belongs to the class of carotenoids, and is very “focused” on reducing free radical-mediated damage to fat, and your brain is 60 or 70 percent fat

The Importance of Vitamin D and Cholesterol for Brain Health

Vitamin D also plays a fundamental role in brain health, immune function, and inflammation. According to Dr. Perlmutter, vitamin D influences the expression of more than 913 genes. Sadly, a vast majority of people are dramatically deficient in this critical steroid hormone, in large part because they’ve been fooled into fearing sun exposure. You’ve also been deceived into fearing cholesterol, which is another critical component of health.

“Obviously, sunshine makes vitamin D in your body from some precursor. When I ask my patients what is that precursor, nobody seems to know. I tell them it’s this horrible thing called cholesterol, and their eyebrows go up,” he says.“Cholesterol is so drastically important for health, because (1) it’s the precursor for which you make vitamin D and (2) it’s a fundamental compound of every cell in your body and made by every cell in your body. It’s a brain antioxidant. It’s a precursor for all the steroid sex hormones – it’s fundamentally important.”

According to Dr. Perlmutter, research shows that elderly individuals with the lowest cholesterol levels have the highest risk for Alzheimer’s. They also have the highest risk for dying. As he says, the war on cholesterol is fundamentally inappropriate and harmful.

“I say to my audiences very frequently, “If cholesterol is so bad, what you’re saying is that if you believe in evolution or if you believe in creation – either way – either nature got it wrong or God got it wrong by putting the ability to make cholesterol in every one of our cells. Why would that be a mistake?”

It’s not a mistake. We are desperate for cholesterol. It’s a fundamental player in every cell membrane. We’ve been on a high-cholesterol diet for millions of years, and it has served us well. In fact, our genome has been selected based upon that diet, being on a high-cholesterol diet – eating eggs, animal fat, and animal protein.”

The Benefits of Fasting

Dr. Perlmutter places most of his patients on a ketogenic, high-fat, low-carbohydrate diet that is gluten-free, along with prescribed aerobic exercise. Certain supplements may also be used, especially if the patient is vitamin D deficient or has any other critical deficiency.

I’ve previously interviewed Dr. Seyfried, who is a researcher at Boston University and connected with Harvard. He was one of the leading investigators to adopt the ketogenic diet for a neurological condition, the treatment of seizures, and then from there started investigating its use for treatment of cancer. Another PhD, Dr. D’Agostino in Florida, is also doing similar work in this area.

It’s interesting to note that it all stemmed from the treatment of intractable seizure disorders; before they realized that it was also a potent treatment adjunct for cancer patients. Most interestingly, cancer cells do not have the ability to any significant degree to metabolize fat and are almost completely dependent on metabolizing sugar. When you go on a ketogenic diet, you effectively deprive the cancer cells of sugar, which starves them, while allowing normal cells to thrive. Beyond that, you also need to recognize that the balance of organisms in your intestine play a critical role in maintaining your immunity. Clearly, if you’re fighting disease of any kind, you want your immune system to function optimally.

“When you damage your microbiom, the balance of bacteria, in your gut by taking chemotherapy, at the very least add in an aggressive probiotic approach to keep bad bacteria count healthy,” Dr. Perlmutter says.

I’m particularly fond of using fermented vegetables, because they can deliver extraordinarily high levels of beneficial bacteria. Most people aren’t aware that in a healthy serving of sauerkraut – two to three ounces or so – you’re getting the equivalent of nearly 100 capsules of the highest-potency probiotic you can buy. It’s clearly one of the most cost-effective alternatives. Furthermore, if it’s fermented with a starter culture, which we’re going to be offering soon, you can also get very high levels of vitamin K2, which is crucial to balance vitamin D.

Dr. Perlmutter also highly recommends fasting. Contrary to popular belief, the ideal fuel for your brain is not glucose but ketones, which is the fat that your body mobilizes when you stop feeding it carbs and introduce coconut oil and other sources of healthy fats into your diet. A one-day fast can help your body to “reset” itself, and start to burn fat instead of sugar. As part of a healthy lifestyle, I prefer an intermittent fasting schedule that simply calls for limiting your eating to a narrower window of time each day. By restricting your eating to a 6-8 hour window, you effectively fast 16-18 hours each day. To learn more, please see this previous article.

“The easiest way to become ketotic is just to stop eating. Because if you go through your sugar stores and then your glycogen stores relatively soon, you begin to burn fat, the most incredibly powerful source of fuel for human physiology and especially for the brain,” he says.

More Information:

To learn more, I highly recommend Dr. Perlmutter’s New York Times Best Selling book, Grain Brain. You can also find more information on his web site, DrPerlmutter.com. You can also find more tips and guidelines in this previous article on Alzheimer’s prevention.

“These changes that people can make in their diets are not draconian,” he says. “The only thing that makes it difficult is because of what we are told by society we should be eating. Those statements are not given to us with good, sound scientific backing. Again, these are simple but profound choices that people can make.”

I couldn’t agree more. Applying the strategies discussed in this interview and article can dramatically reduce your risk of succumbing to Alzheimer’s and other chronic diseases. Overall, it will also raise your general quality of life. Clearly, prevention is much easier than treating it after the fact. And even though there is this element of neuroplasticity, it’s far better to prevent brain degeneration to begin with. As Dr. Perlutter says:

“The time to fix the roof is when the sun is shining. That’s the segment of the population I really want to target – people who have not yet had cognitive issues but are at risk, which is basically all of us. In fact, this is the time to make the changes – while you’re still healthy. Time to cut back on the carbohydrates, increase your consumption of good fats, get out and exercise… these are the fundamentals that could keep these problems from happening in the first place.”

Source: http://articles.mercola.com/sites/articles/archive/2013/09/29/dr-perlmutter-gluten.aspx

Posted in Causes, Diet, Grain Brain, Treatments | Leave a comment